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The size distribution of homozygous segments in the human genome.

作者信息

Clark A G

出版信息

Am J Hum Genet. 1999 Dec;65(6):1489-92. doi: 10.1086/302668.

DOI:10.1086/302668
PMID:10577901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1288358/
Abstract
摘要

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本文引用的文献

1
ON THE RELATIVE ABUNDANCE OF BIRD SPECIES.论鸟类物种的相对丰富度。
Proc Natl Acad Sci U S A. 1957 Mar 15;43(3):293-5. doi: 10.1073/pnas.43.3.293.
2
Linkage disequilibrium, gene trees and selfing: an ancestral recombination graph with partial self-fertilization.连锁不平衡、基因树与自交:具有部分自体受精的祖先重组图
Genetics. 2000 Feb;154(2):923-9. doi: 10.1093/genetics/154.2.923.
3
Long homozygous chromosomal segments in reference families from the centre d'Etude du polymorphisme humain.来自人类多态性研究中心的参考家族中的长纯合染色体片段。
Am J Hum Genet. 1999 Dec;65(6):1493-500. doi: 10.1086/302661.
4
Maternal uniparental disomy of chromosome 14 confined to an interstitial segment (14q23-14q24.2).局限于间质段(14q23 - 14q24.2)的母源性14号染色体单亲二体性。
J Med Genet. 1999 Aug;36(8):633-6.
5
Complete androgen insensitivity in a 47,XXY patient with uniparental disomy for the X chromosome.
Am J Med Genet. 1999 Sep 10;86(2):107-11. doi: 10.1002/(sici)1096-8628(19990910)86:2<107::aid-ajmg3>3.0.co;2-4.
6
Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping.通过单倍型共享的衰减评估连锁不平衡及其在精细尺度基因定位中的应用。
Am J Hum Genet. 1999 Sep;65(3):858-75. doi: 10.1086/302537.
7
Recombination as a point process along sequences.作为沿序列的点过程的重组。
Theor Popul Biol. 1999 Jun;55(3):248-59. doi: 10.1006/tpbi.1998.1403.
8
Maximum-likelihood estimation of migration rates and effective population numbers in two populations using a coalescent approach.使用溯祖方法对两个种群的迁移率和有效种群数量进行最大似然估计。
Genetics. 1999 Jun;152(2):763-73. doi: 10.1093/genetics/152.2.763.
9
The time to the ancestor along sequences with recombination.沿着带有重组的序列追溯到祖先的时间。
Theor Popul Biol. 1999 Apr;55(2):137-44. doi: 10.1006/tpbi.1998.1390.
10
Sequence variation in the human angiotensin converting enzyme.人类血管紧张素转换酶的序列变异
Nat Genet. 1999 May;22(1):59-62. doi: 10.1038/8760.