恒河猴的结节部分泌促黄体生成素。
The pars tuberalis of the rhesus monkey secretes luteinizing hormone.
作者信息
Antunes J L, Carmel P W, Zimmerman E A, Ferin M
出版信息
Brain Res. 1979 Apr 20;166(1):49-55. doi: 10.1016/0006-8993(79)90648-6.
The presence of luteinizing hormone within the pars tuberalis of the adenohypophysis and its secretion into pituitary stalk vessels were investigated in adult rhesus monkeys. Portal blood was collected in 9 monkeys, after section of the pituitary stalk. In 22 out of 26 samples, portal to peripheral LH ratios, as measured by radioimmunoassay, ranged from 2 to 48. Portal LH levels were highest in 3 animals studied at the time of the midcycle surge. No differences between portal and peripheral growth hormone (GH) and prolactin levels were observed. Immunocytochemical studies in 4 normal and 3 ovariectomized female monkeys indicated that LH, but not GH, prolactin or thyroid stimulating hormone were present within the pars tuberalis. Cells containing these hormones were identified within the pars distalis. These results indicate that the pars tuberalis forms and secretes LH via the hypophyseal portal circulation.
在成年恒河猴中，研究了腺垂体结节部促黄体生成素（LH）的存在及其向垂体柄血管的分泌情况。在9只猴子中，切断垂体柄后采集门脉血。通过放射免疫测定法测量，在26个样本中的22个样本中，门脉与外周LH的比率在2至48之间。在月经周期中期高峰时研究的3只动物中，门脉LH水平最高。未观察到门脉与外周生长激素（GH）和催乳素水平之间的差异。对4只正常雌性猴子和3只去卵巢雌性猴子的免疫细胞化学研究表明，结节部存在LH，但不存在GH、催乳素或促甲状腺激素。在远侧部鉴定出含有这些激素的细胞。这些结果表明，结节部通过垂体门脉循环形成并分泌LH。
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