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绵羊结节部:一项免疫组织化学研究。糖蛋白和促脂解激素的存在证明。

The sheep pars tuberalis: an immunohistochemical study. Demonstration of the presence of glycoprotein and lipotropin hormones.

作者信息

Tillet Y, Pelletier J, Tramu G, de Reviers M M

机构信息

Laboratoire de Neuroendocrinologie Sexuelle, INRA, Nouzilly, France.

出版信息

Histochemistry. 1990;94(4):403-8. doi: 10.1007/BF00266447.

Abstract

Using indirect immunofluorescence with fourteen different antisera raised against pituitary hormones and peptides, we characterized immunochemically the cells of the sheep pars tuberalis. The presence of LH- and FSH-containing cells, shown in previous studies, was also observed in the present investigation. In addition, we found TSH-containing cells, never observed in sheep, and beta LPH-containing cells. The latter hormone has never been found in any studied species. It appeared that a small amount of perikarya (less than 20%) were immunolabelled and, that the sheep pars tuberalis contained a majority of immunonegative cells as in the guinea-pig rabbit and rhesus monkey. This study may contribute to a better knowledge of the function of the sheep pars tuberalis.

摘要

我们使用针对垂体激素和肽产生的14种不同抗血清进行间接免疫荧光法,对绵羊结节部的细胞进行了免疫化学特征分析。在本研究中也观察到了先前研究中显示的含促黄体生成素(LH)和促卵泡生成素(FSH)的细胞。此外,我们发现了在绵羊中从未观察到的含促甲状腺激素(TSH)的细胞以及含β-促脂素(βLPH)的细胞。后一种激素在任何研究过的物种中都从未被发现。似乎有少量的核周体(少于20%)被免疫标记,并且绵羊结节部像豚鼠、兔子和恒河猴一样含有大多数免疫阴性细胞。这项研究可能有助于更好地了解绵羊结节部的功能。

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