基因距离的基因座间变异与中性突变理论。
Interlocus variation of genetic distance and the neutral mutation theory.
作者信息
Nei M, Tateno Y
出版信息
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2758-60. doi: 10.1073/pnas.72.7.2758.
Abstract
Theoretical distributions of genetic distance between reproductively isolated taxa are derived by means of computer simulation, taking into account mutation and random genetic drift. The distributions obtained are in good agreement with the observed distributions of interracial and interspecific genetic distances for enzymes loci in Drosophila. This indicates that the gene substitution at enzyme loci can be explained by the neutral mutation theory.
摘要
通过计算机模拟，考虑到突变和随机遗传漂变，得出了生殖隔离类群之间遗传距离的理论分布。所得分布与果蝇中酶基因座的种间和种内遗传距离的观察分布高度一致。这表明酶基因座上的基因替代可以用中性突变理论来解释。
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