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本文引用的文献

1
The accumulation of genetic variability in yeast.酵母中遗传变异性的积累。
Genetics. 1971 Aug;68(4):547-57. doi: 10.1093/genetics/68.4.547.
2
Comparison of genetical and morphological methods for a study of biological differences.用于生物学差异研究的遗传学和形态学方法比较。
Am J Phys Anthropol. 1953 Sep;11(3):385-404. doi: 10.1002/ajpa.1330110313.
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Phylogenetic analysis. Models and estimation procedures.系统发育分析。模型与估计程序。
Am J Hum Genet. 1967 May;19(3 Pt 1):233-57.
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Bioassay of kinship.亲属关系生物测定
Theor Popul Biol. 1971 Dec;2(4):507-24. doi: 10.1016/0040-5809(71)90038-4.

杂合性与遗传距离的抽样方差。

Sampling variances of heterozygosity and genetic distance.

作者信息

Nei M, Roychoudhury A K

出版信息

Genetics. 1974 Feb;76(2):379-90. doi: 10.1093/genetics/76.2.379.

DOI:10.1093/genetics/76.2.379
PMID:4822472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213072/
Abstract

Mathematical formulae for the sampling variances of average heterozygosity and Nei's genetic distance are developed. These sampling variances are decomposed into their two components, i.e. the inter-locus and intra-locus variances. The relationship between the number of loci and the number of individuals per locus to be examined for estimating average heterozygosity and genetic distance is also discussed. The utility of the inter-locus variance of heterozygosity for studying the mechanism of maintenance of genetic variability in populations is indicated.

摘要

推导了平均杂合度和内氏遗传距离抽样方差的数学公式。这些抽样方差被分解为两个组成部分,即位点间方差和位点内方差。还讨论了用于估计平均杂合度和遗传距离时所检测的位点数与每个位点个体数之间的关系。指出了杂合座位间方差在研究群体遗传变异性维持机制方面的用途。