Hitzig W H
Schweiz Med Wochenschr. 1975 Aug 23;105(34):1088-92.
Acute leukemias of childhood differ considerably from the adult type with regard to clinical and laboratory findings as well as prognosis (Tables 1-3). Therapeutic progress (Table 4) within the last two decades has resulted not only in remarkable palliation, but increasingly also in true cure. However, this development appears to be far from complete, and to think in terms of a definitive scheme of treatment is therefore misleading and dangerous. On the contrary, work in cooperative study groups aiming at further therapeutic improvement must continue. All children with leukemia in Switzerland may benefit from the advances offered by such studies if they are initially admitted to one of our centers of pediatric oncology. Further control and follow-up, however, can continue to be carried out on a decentralized basis by practicing pediatricians and hematologists.
儿童急性白血病在临床和实验室检查结果以及预后方面与成人型有很大差异（表1 - 3）。过去二十年的治疗进展（表4）不仅带来了显著的症状缓解，而且越来越多地实现了真正的治愈。然而，这一进展似乎远未完成，因此按照确定的治疗方案来思考是误导性的且危险的。相反，旨在进一步改善治疗的合作研究小组的工作必须继续。瑞士所有白血病患儿如果最初被收治到我们的儿科肿瘤中心之一，都可能从这类研究取得的进展中受益。不过，进一步的管控和随访可以继续由执业儿科医生和血液科医生在分散的基础上进行。
