Jose D G
Aust N Z J Med. 1975 Aug;5(4):318-23. doi: 10.1111/j.1445-5994.1975.tb03265.x.
A beneficial clinical effect from the administration of lymphocyte transfer factor is described in six patients with idiopathic early onset chronic muco-cutaneous candidiasis. Five patients in two families showed a familial disease pattern. Dermal anergy and failure to produce migratory inhibition factor with intact general immune function were found in patients tested. Antifungal chemotherapy was effective in clearing or markedly reducing the candidiasis and remission was maintained by repeated injections of transfer factor. Therapy was monitored using Candida skin test.
六位特发性早发性慢性黏膜皮肤念珠菌病患者接受淋巴细胞转移因子治疗后出现了有益的临床效果。两个家族中的五位患者呈现出家族性疾病模式。对患者进行检测发现,其存在皮肤无反应性,且在整体免疫功能完好的情况下无法产生游走抑制因子。抗真菌化疗在清除念珠菌病或显著减轻病情方面有效,通过反复注射转移因子维持了缓解状态。使用念珠菌皮肤试验对治疗进行监测。