Dunn P J, Donald R A, Espiner E A
Aust N Z J Med. 1975 Aug;5(4):369-72. doi: 10.1111/j.1445-5994.1975.tb03275.x.
A case of acromegaly complicated by pituitary apoplexy is described. The pituitary apoplexy occurred while the patient was under investigation in a metabolic ward permitting full assessment of pituitary function both before and immediately after the event. This demonstrated a remarkably selective reduction in the plasma growth hormone concentration with preservation of other pituitary function excluding mild diabetes insipidus. The plasma growth hormone fell from values greater than 120 ng/ml to less than 4 ng/ml. The brisk inappropriate release of growth hormone observed on stimulation with thyrotrophic hormone releasing hormone, associated with a severe headache and the onset of pituitary apoplexy two days later raised the possibility of provocative tests of pituitary function precipitating pituitary apoplexy.
本文描述了一例肢端肥大症合并垂体卒中的病例。垂体卒中发生在患者于代谢病房接受检查期间，这使得在事件发生前和发生后即刻能够对垂体功能进行全面评估。结果显示，血浆生长激素浓度显著选择性降低，而其他垂体功能得以保留，但存在轻度尿崩症。血浆生长激素水平从高于120 ng/ml降至低于4 ng/ml。促甲状腺激素释放激素刺激试验时观察到生长激素的快速不适当释放，同时伴有严重头痛，并在两天后发生垂体卒中，这增加了垂体功能激发试验诱发垂体卒中的可能性。
