Jaffé A, Bush A
Department of Respiratory Paediatrics, Royal Brompton Hospital, London, UK.
Pediatr Pulmonol. 1999 Dec;28(6):449-50. doi: 10.1002/(sici)1099-0496(199912)28:6<449::aid-ppul11>3.0.co;2-h.
Ciprofloxacin, a quinolone antibiotic, is used to treat a wide variety of infections including Pseudomonas aeruginosa in patients with cystic fibrosis (CF). Photosensitivity is a well-known complication of treatment with this group of antibiotics, and it is more common in patients with CF. We report on a case of photosensitivity induced by indoor fluorescent strip-lighting (spectral range, 295-760 nm) in a 12-year-old girl with CF treated with ciprofloxacin. This type of lighting emits UVA rays (320-400 nm) which cause skin damage in the presence of sensitizing agents. Patients taking ciprofloxacin are usually advised to protect their skin from direct sunlight. We suggest that more attention should be paid to indoor sources of UV light.
环丙沙星是一种喹诺酮类抗生素,用于治疗多种感染,包括囊性纤维化(CF)患者的铜绿假单胞菌感染。光敏反应是这类抗生素治疗中一种广为人知的并发症,在CF患者中更为常见。我们报告了一例12岁CF女童在用环丙沙星治疗期间,因室内荧光灯带照明(光谱范围295 - 760纳米)诱发光敏反应的病例。这类照明会发出紫外线A(320 - 400纳米),在存在致敏剂的情况下会导致皮肤损伤。服用环丙沙星的患者通常会被建议保护皮肤免受阳光直射。我们建议应更多关注室内紫外线光源。