Mais D D, Mulhall B P, Adolphson K R, Yamamoto K
Department of Pathology, Madigan Army Medical Center, Tacoma, WA 98431-5000, USA.
Am J Clin Pathol. 1999 Dec;112(6):810-5. doi: 10.1093/ajcp/112.6.810.
Autoimmune enteropathy is an increasingly recognized cause of severe protracted diarrhea, usually affecting infants and children predisposed to autoimmune phenomena. Although this may be a common cause of diarrheal illness, it is scarcely recognized in the American literature. In association with thymoma, a case of so-called graft-vs-host-like colitis and 2 cases of chronic diarrhea associated with thymoma were reported, but, to our knowledge, no cases of autoimmune enteropathy have been reported as such. We describe 2 adults with autoimmune enteropathy found in association with a thymoma.
自身免疫性肠病是严重持续性腹泻日益被认识到的病因,通常影响易患自身免疫现象的婴幼儿。尽管这可能是腹泻性疾病的常见病因,但在美国文献中却很少被认识到。曾有报道1例与胸腺瘤相关的所谓移植物抗宿主样结肠炎以及2例与胸腺瘤相关的慢性腹泻,但据我们所知,尚无自身免疫性肠病的此类报道。我们描述2例与胸腺瘤相关的自身免疫性肠病成年患者。