Merrill J, Alterman A, Cacciola J, Rutherford M
Treatment Research Institute, University of Pennsylvania School of Medicine, Philadelphia 19103, USA.
J Subst Abuse Treat. 1999 Dec;17(4):313-9. doi: 10.1016/s0740-5472(99)00012-4.
This study examines the hypothesis that treatment is a cumulative process; that is, treatment success is best viewed in terms of the patient's entire treatment history, rather than the index treatment episode. Three-hundred and eight patients with a primary heroin addiction were studied for 2 years posttreatment. Using posttreatment arrests as the dependent variable, the effects of prior treatment were assessed. Those with six or more prior treatment episodes and who had been in treatment for 12 or more months during the most recent episode averaged only 0.2 arrests in the 2 years posttreatment, while those with no prior treatment, but 12 or more months in the recent treatment averaged 0.88 arrests. Logistic analysis found that each prior treatment reduced the probability of a posttreatment arrest by 25%. Based on a linear regression, patients with six or more treatments prior treatments averaged half the number of posttreatment arrests as someone with no treatments before the index episode.
本研究检验了治疗是一个累积过程的假设；也就是说，治疗成功最好从患者的整个治疗史角度来看待，而不是从本次治疗发作来看。对308名原发性海洛因成瘾患者进行了治疗后2年的研究。以治疗后的逮捕情况作为因变量，评估先前治疗的效果。那些有6次或更多先前治疗发作且在最近一次发作期间接受治疗12个月或更长时间的患者，在治疗后2年平均只有0.2次被捕，而那些没有先前治疗但最近治疗12个月或更长时间的患者平均有0.88次被捕。逻辑分析发现，每次先前治疗会使治疗后被捕的概率降低25%。基于线性回归，有6次或更多先前治疗的患者治疗后被捕的平均次数是在本次发作前没有治疗的患者的一半。
