泪囊孤立性纤维瘤
Solitary fibrous tumor of the lacrimal sac.
作者信息
Woo K I, Suh Y L, Kim Y D
机构信息
Department of Ophthalmology, Sungkyunkwan University College of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.
出版信息
Ophthalmic Plast Reconstr Surg. 1999 Nov;15(6):450-3. doi: 10.1097/00002341-199911000-00018.
PURPOSE
Solitary fibrous tumor is a rare spindle cell tumor arising in the pleura. We report two cases of this tumor occurring in the lacrimal sac.
METHODS
A 23-year-old man and a 34-year-old woman presented with a medial canthal mass. They underwent surgical excision of their tumors.
RESULTS
Solitary fibrous tumors were diagnosed by light microscopy, immunohistochemical study, and electron microscopy. Immunohistochemical staining showed that tumor cells were reactive with vimentin and CD34 and demonstrated no smooth muscle or neural differentiation (nonreactive with desmin and S-100 protein).
CONCLUSIONS
The findings indicate that solitary fibrous tumor can occur in the lacrimal sac and may recur locally if it is removed incompletely. To our knowledge, these are the first reported cases of solitary fibrous tumors occurring in the lacrimal sac.
目的
孤立性纤维瘤是一种起源于胸膜的罕见梭形细胞肿瘤。我们报告两例发生于泪囊的该肿瘤病例。
方法
一名23岁男性和一名34岁女性因内眦肿物就诊。他们均接受了肿瘤手术切除。
结果
通过光镜检查、免疫组化研究及电镜检查确诊为孤立性纤维瘤。免疫组化染色显示肿瘤细胞对波形蛋白和CD34呈阳性反应，且未显示平滑肌或神经分化（对结蛋白和S-100蛋白呈阴性反应）。
结论
这些发现表明孤立性纤维瘤可发生于泪囊，若切除不完全可能局部复发。据我们所知，这些是首次报道的发生于泪囊的孤立性纤维瘤病例。
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