[Focal morphological changes in the bone tissue of the mandible and tibia of rabbits under the influence of different metal inclusions].

Morphological changes in bone tissue were studied in an experimental model with electrochemical polarization of the bone, which was achieved by applying electrodes (anode made of silver-palladium alloy SPS-250 and cathode of copper-aluminum alloy manufactured as orthodontic ligature wire) on the mandibular periosteum and tibial bone of rabbits. Macroscopic changes were as follows: osseous tissue hypertrophy at the zone of cathode polarization with a corresponding increase in the area of transverse section of the mandible and atrophy of the bone under the anode, all this causing pronounced asymmetry of the jaw bones. Microscopic changes in the bone were adequate to the macroscopic and characterized by sharp activation of its apposition (under cathode) and resorption (under anode).