Helmbold P, Rompel R, Petres J, Lübbe D, Marsch W C
Klinik und Poliklinik für Hautkrankheiten, Martin-Luther-Universität Halle-Wittenberg, Halle/Saale.
Hautarzt. 1999 Nov;50(11):779-84. doi: 10.1007/s001050050984.
Congenital melanocytic nevi are benign skin tumours with a population-based prevalence of 1-6%. They run an increased life-time risk of transformation into malignant melanoma. Additionally, they can be associated with an involvement of the leptomeninges (neurocutaneous melanosis), and may cause considerable cosmetic and psychic problems. In contrast to the past, the risk of congenital melanocytic nevi developing into melanoma is now regarded as well-established. Thus, excision is recommended whenever possible. Large lesions which do not allow complete excision should be treated by dermabrasion within the first weeks of life.
先天性黑素细胞痣是一种良性皮肤肿瘤,人群患病率为1%-6%。它们发生恶性黑色素瘤转化的终生风险增加。此外,它们可能与软脑膜受累(神经皮肤黑素沉着症)有关,并可能导致相当严重的美容和心理问题。与过去不同,现在认为先天性黑素细胞痣发展成黑色素瘤的风险是确凿的。因此,建议尽可能进行切除。无法完全切除的大病灶应在出生后的头几周内通过磨皮术进行治疗。