Konz B
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, München, Deutschland.
Hautarzt. 2007 Aug;58(8):659-60, 662-6, 668-70. doi: 10.1007/s00105-007-1354-5.
Congenital melanocytic nevi are rare lesions which depending on their size and location may cause major cosmetic and psychological problems. Large congenital melanocytic nevi may undergo malignant change and can also be associated with neurocutaneous melanosis. The different treatment approaches reach different levels of the skin. Complete excision is the treatment of choice, but is not always possible with giant nevi. Superficial treatment can reduce the pigmentation, but repigmentation is not uncommon. Incomplete removal of melanocytic nevi does not reduce the melanoma risk. Surgical intervention must be carefully planned; the advantages and disadvantages of the different modalities must be discussed with the parents. The risk of malignant transformation must be weighed up against the expected aesthetic and functional outcomes.
先天性黑素细胞痣是罕见的病变，根据其大小和位置，可能会导致严重的美容和心理问题。大型先天性黑素细胞痣可能会发生恶变，也可能与神经皮肤黑素沉着症有关。不同的治疗方法作用于皮肤的不同层次。完整切除是首选的治疗方法，但对于巨大痣并不总是可行。浅表治疗可以减少色素沉着，但色素再沉着并不少见。黑素细胞痣切除不完全并不能降低患黑色素瘤的风险。手术干预必须精心规划；必须与家长讨论不同治疗方式的优缺点。必须权衡恶变风险与预期的美学和功能结果。
