成年期皮肤磨削术后20年，巨大先天性黑素细胞痣发生多中心恶性黑色素瘤。
Multicentric malignant melanoma in a giant melanocytic congenital nevus 20 years after dermabrasion in adulthood.
作者信息
Zutt Markus, Kretschmer Lutz, Emmert Steffen, Haenssle Holger, Neumann Christine, Bertsch Hans Peter
机构信息
Department of Dermatology, University of Goettingen, Goettingen, Germany.
出版信息
Dermatol Surg. 2003 Jan;29(1):99-101; discussion 101. doi: 10.1046/j.1524-4725.2003.29007.x.
BACKGROUND
Dermabrasion is one approach to the treatment of treating giant melanocytic congenital nevi. Treatment is recommended to reduce the risk of spontaneous malignant transformation of giant nevi into malignant melanomas that usually occur in childhood.
OBJECTIVE
To describe the development of a multicentric malignant melanoma in a giant melanocytic congenital nevus after dermabrasion.
METHODS
We report about a 46-year-old male patient who developed a multicentric malignant melanoma in a giant melanocytic congenital nevus. The nevus was located on his left shoulder extending to his neck and chest. Previously, dermabrasion of the nevus was performed twice at the ages of 26 and 28.
RESULTS
To our knowledge, this is the first report of malignant transformation of a giant nevus into a multicentric malignant melanoma diagnosed 20 years after the procedure of dermabrasion.
CONCLUSION
We conclude that a close follow-up of such patients is mandatory.
背景
磨皮术是治疗巨大先天性黑素细胞痣的一种方法。建议进行治疗以降低巨大痣在儿童期通常会自发恶变成为恶性黑色素瘤的风险。
目的
描述磨皮术后巨大先天性黑素细胞痣中多中心恶性黑色素瘤的发生情况。
方法
我们报告了一名46岁男性患者，其在巨大先天性黑素细胞痣中发生了多中心恶性黑色素瘤。该痣位于他的左肩，延伸至颈部和胸部。此前，该痣在他26岁和28岁时进行了两次磨皮术。
结果
据我们所知，这是第一例关于磨皮术后20年诊断出巨大痣恶变成为多中心恶性黑色素瘤的报告。
结论
我们得出结论，对此类患者进行密切随访是必要的。
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