Salgado H, Santos-Zavaleta A, Gama-Castro S, Millán-Zárate D, Blattner F R, Collado-Vides J
Centro de Investigación sobre Fijación de Nitrógeno, UNAM A.P. 565-A Cuernavaca, Morelos 62100, México.
Nucleic Acids Res. 2000 Jan 1;28(1):65-7. doi: 10.1093/nar/28.1.65.
RegulonDB is a database on transcription regulation and operon organization in Escherichia coli. The current version describes regulatory signals of transcription initiation, promoters, regulatory binding sites of specific regulators, ribosome binding sites and terminators, as well as information on genes clustered in operons. These specific annotations have been gathered from a constant search in the literature, as well as based on computational sequence predictions. The genomic coordinates of all these objects in the E.coli K-12 chromosome are clearly indicated. Every known object has a link to at least one MEDLINE reference. We have also added direct links to recent expression data of E.coli K-12. The version presented here has important modifications both in the structure of the database, as well as in the amount and type of information encoded in the database. RegulonDB can be accessed on the web at URL: http://www.cifn.unam. mx/Computational_Biology/regulondb/
RegulonDB是一个关于大肠杆菌转录调控和操纵子组织的数据库。当前版本描述了转录起始的调控信号、启动子、特定调控因子的调控结合位点、核糖体结合位点和终止子，以及操纵子中基因簇的信息。这些特定注释是通过在文献中不断搜索以及基于计算序列预测收集而来的。大肠杆菌K-12染色体中所有这些对象的基因组坐标都有明确标注。每个已知对象都至少有一个指向MEDLINE参考文献的链接。我们还添加了指向大肠杆菌K-12近期表达数据的直接链接。此处展示的版本在数据库结构以及数据库中编码的信息量和信息类型方面都有重要修改。可通过以下网址在网上访问RegulonDB：http://www.cifn.unam. mx/Computational_Biology/regulondb/
