III期和IV期子宫内膜异位症患者体外受精-胚胎移植的结局比输卵管性不孕患者更差。
Patients with stages III and IV endometriosis have a poorer outcome of in vitro fertilization-embryo transfer than patients with tubal infertility.
作者信息
Azem F, Lessing J B, Geva E, Shahar A, Lerner-Geva L, Yovel I, Amit A
机构信息
IVF-ET Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel.
出版信息
Fertil Steril. 1999 Dec;72(6):1107-9. doi: 10.1016/s0015-0282(99)00392-1.
OBJECTIVE
To evaluate the outcome of IVF in patients with stages III and IV endometriosis.
DESIGN
Retrospective study.
SETTING
The Sara Racine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel.
PATIENT(S): Fifty-eight patients with stages III and IV endometriosis and 60 patients with tubal infertility.
INTERVENTION(S): IVF-ET for all couples.
MAIN OUTCOME MEASURE(S): Fertilization, pregnancy, and birth rates.
RESULT(S): The comparison between patients with endometriosis and those with tubal infertility indicated that the former had a poor IVF outcome in terms of reduced fertilization rate (40% vs. 70%), reduced pregnancy rate per cycle (10.6% vs. 22.4%), and reduced birth rate per cycle (6.7% vs. 16.6%). The differences were statistically significant.
CONCLUSION(S): The results show an unfavorable outcome of IVF-ET in patients with endometriosis when compared with those who have tubal infertility.
目的
评估Ⅲ期和Ⅳ期子宫内膜异位症患者体外受精（IVF）的结果。
设计
回顾性研究。
地点
以色列特拉维夫索拉斯基医学中心利斯妇产医院的萨拉·拉辛IVF中心。
患者
58例Ⅲ期和Ⅳ期子宫内膜异位症患者以及60例输卵管性不孕症患者。
干预措施
所有夫妇均接受体外受精-胚胎移植（IVF-ET）。
主要观察指标
受精率、妊娠率和出生率。
结果
子宫内膜异位症患者与输卵管性不孕症患者的比较表明，前者在IVF结果方面较差，表现为受精率降低（40%对70%）、每个周期的妊娠率降低（10.6%对22.4%）以及每个周期的出生率降低（6.7%对16.6%）。差异具有统计学意义。
结论
结果显示，与输卵管性不孕症患者相比，子宫内膜异位症患者进行IVF-ET的结果不佳。
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