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Dynamic evaluation of prolactin secretion in patients with oligospermia: effects of treatment with metergoline.

作者信息

Masala A, Delitala G, Alagna S, Devilla L, Rovasio P P, Lotti G

出版信息

Fertil Steril. 1979 Jan;31(1):63-7. doi: 10.1016/s0015-0282(16)43762-3.

DOI:10.1016/s0015-0282(16)43762-3
PMID:105938
Abstract

Serum prolactin levels were measured in 50 patients with oligospermia and in 20 control subjects under fasting conditions and following the administration of levodopa, pyridoxine, metoclopramide, and synthetic thyrotropin-releasing hormone. Four patients (8%) under fasting conditions had prolactin levels slightly above the normal range. However, no significant differences in prolactin behavior were detected between patients with hyperprolactinemia, patients with normal prolactin levels, and control subjects. The four patients with hyperprolactinemia were treated with metergoline, an ergoline derivative. Metergoline administration promptly reduced the prolactin levels. Spermatogenesis was restored in three patients after 4 to 5 months of treatment.

摘要

相似文献

1
Dynamic evaluation of prolactin secretion in patients with oligospermia: effects of treatment with metergoline.
Fertil Steril. 1979 Jan;31(1):63-7. doi: 10.1016/s0015-0282(16)43762-3.
2
Effects of long-term treatment with metergoline in patients with idiopathic oligospermia.麦角苄酯长期治疗特发性少精子症患者的效果。
Clin Endocrinol (Oxf). 1979 Sep;11(3):349-52. doi: 10.1111/j.1365-2265.1979.tb03084.x.
3
Treatment of hyperprolactinemic amenorrhea with Metergoline.用麦角苄酯治疗高催乳素血症性闭经。
Obstet Gynecol. 1986 Feb;67(2):249-52. doi: 10.1097/00006250-198602000-00016.
4
Hyperprolactinemic primary amenorrhea: case report with successful prolactin-lowering treatment and review of the literature.高催乳素血症性原发性闭经:催乳素降低治疗成功的病例报告及文献综述
Gynecol Obstet Invest. 1980;11(6):317-26. doi: 10.1159/000299853.
5
Metergoline as an inhibitor of prolactin release.美麦角林作为催乳素释放抑制剂。
J Reprod Med. 1987 Feb;32(2):115-9.
6
[Metergoline in hyperprolactinemic breast cancer: a phase II study].
Onkologie. 1986 Oct;9(5):245-8. doi: 10.1159/000216020.
7
[Effect of pretreatment with metoclopramide on plasma prolactin response to methergoline].[胃复安预处理对血浆催乳素对麦角新碱反应的影响]
Boll Soc Ital Biol Sper. 1979 Dec 30;55(24):2575-81.
8
Metergoline and bromocriptine in the management of tumoral and idiopathic hyperprolactinemia.美麦角林和溴隐亭用于治疗肿瘤性和特发性高泌乳素血症
Horm Metab Res. 1983 Aug;15(8):380-4. doi: 10.1055/s-2007-1018730.
9
Restoration of cyclic ovarian function by metergoline treatment in a patient with a prolactin-secreting pituitary microadenoma.用麦角苄酯治疗分泌催乳素的垂体微腺瘤患者,恢复其卵巢周期性功能。
Fertil Steril. 1978 Aug;30(2):237-9. doi: 10.1016/s0015-0282(16)43466-7.
10
Metergoline inhibition of thyrotrophin and prolactin secretions in primary hypothyroidism.美麦角林对原发性甲状腺功能减退症中促甲状腺激素和催乳素分泌的抑制作用。
Clin Endocrinol (Oxf). 1978 Jan;8(1):69-73. doi: 10.1111/j.1365-2265.1978.tb01351.x.

引用本文的文献

1
Parlodel treatment of patients with pathospermia.用溴隐亭治疗精子活力低下患者。
Int Urol Nephrol. 1982;14(3):307-12. doi: 10.1007/BF02081817.
2
Testicular dysfunction in men with sickle cell disease.镰状细胞病男性的睾丸功能障碍
Postgrad Med J. 1987 Feb;63(736):95-8. doi: 10.1136/pgmj.63.736.95.