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[Metergoline in hyperprolactinemic breast cancer: a phase II study].

作者信息

Holtkamp W, Nagel G A

出版信息

Onkologie. 1986 Oct;9(5):245-8. doi: 10.1159/000216020.

DOI:10.1159/000216020
PMID:3101016
Abstract

The prolactin release inhibiting action of the dopamine receptor agonist metergoline was investigated in 16 patients with metastatic breast cancer associated with hyperprolactinemia. At a daily dose of 12 mg p.o. for 30 days, the drug was highly effective in lowering prolactin levels (day 0: 1076 +/- 171, day 29: 249 +/- 46 mU/l) in these patients. Starting treatment with 4 mg/day, the side effects of the treatment were mild, including dizziness and nausea.

摘要

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