Freeman S, Stephens R
Skin and Cancer Foundation, Darlinghurst, Australia.
Am J Contact Dermat. 1999 Dec;10(4):198-200. doi: 10.1053/AJCD01000198.
Cheilitis is a common problem, the cause of which is often obscure.
Data on 75 cases of recalcitrant cheilitis were analyzed. These had been referred to a tertiary care center.
Each of the 75 patients had undergone a detailed history, physical examination, and patch tests.
Of the patients, 53 were female (67%), and the age range was 9 to 79 years. Of the cases, 36% included irritant contact dermatitis (ICD), 25% included allergic contact dermatitis (ACD), 19% were attributed to atopic eczema, and in 9% the dermatitis was of unknown cause. Nine percent were noneczematous. The materials causing ACD were medicaments applied to the lips, lipstick ingredients, sunscreen agents, toothpaste ingredients, colophony in dental floss and toothpicks, nail varnish, cosmetics, and nickel in the mouthpiece of a flute.
The most common cause of cheilitis was irritation, frequently caused by liplicking. About one quarter was caused by ACD. Medicaments, lipsticks, sunscreens, and toothpaste were the most common allergens. Atopic eczema is a commonly overlooked cause of cheilitis. However, there is a troublesome group of patients, 9% in this series, who are often severely affected, but the cause of their cheilitis remains obscure.
唇炎是一个常见问题,其病因往往不明。
对75例顽固性唇炎病例的数据进行分析。这些病例均转诊至三级医疗中心。
75例患者均接受了详细的病史询问、体格检查及斑贴试验。
患者中女性53例(67%),年龄范围为9至79岁。病例中,36%为刺激性接触性皮炎(ICD),25%为过敏性接触性皮炎(ACD),19%归因于特应性湿疹,9%的皮炎病因不明。9%为非湿疹性。引起ACD的物质有涂于唇部的药物、口红成分、防晒剂、牙膏成分、牙线和牙签中的松香、指甲油、化妆品以及长笛吹口处的镍。
唇炎最常见的病因是刺激,常由舔唇引起。约四分之一由ACD引起。药物、口红、防晒剂和牙膏是最常见的变应原。特应性湿疹是唇炎一个常被忽视的病因。然而,有一组棘手的患者,本系列中占9%,他们常受到严重影响,但其唇炎病因仍不明。