Kehlet H, Werner M, Perkins F
Department of Surgical Gastroenterology, Hvidovre University Hospital, Denmark.
Drugs. 1999 Nov;58(5):793-7. doi: 10.2165/00003495-199958050-00002.
The concept of balanced analgesia was introduced to improve analgesic efficacy and reduce adverse effects. A large amount of clinical data has documented improved analgesia by combining different analgesics, but data on reducing adverse effects are inconclusive. Balanced analgesia should be used whenever possible, and future studies should be directed to define optimal combination regimens in individual surgical procedures.
平衡镇痛的概念是为了提高镇痛效果和减少不良反应而引入的。大量临床数据证明,联合使用不同的镇痛药可改善镇痛效果,但关于减少不良反应的数据尚无定论。应尽可能采用平衡镇痛,未来的研究应致力于确定针对个别外科手术的最佳联合用药方案。