Kim Saeyoung, Jeon Younghoon, Lee Hyeonjun, Lim Jung A, Park Sungsik, Kim Si Oh
Department of Anesthesiology and Pain Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Anesthesiology and Pain Medicine, School of Dentistry, Kyungpook National University, Daegu, Korea.
J Dent Anesth Pain Med. 2016 Dec;16(4):289-294. doi: 10.17245/jdapm.2016.16.4.289. Epub 2016 Dec 31.
Control of postoperative pain is an important aspect of postoperative patient management. Among the methods of postoperative pain control, patient-controlled analgesia (PCA) has been the most commonly used. This study tested the convenience and safety of a PCA method in which the dose adjusted according to time.
This study included 100 patients who had previously undergone orthognathic surgery, discectomy, or total hip arthroplasty, and wished to control their postoperative pain through PCA. In the test group (n = 50), the rate of infusion was changed over time, while in the control group (n = 50), drugs were administered at a fixed rate. Patients' pain scores on the visual analogue scale, number of rescue analgesic infusions, side effects, and patients' satisfaction with analgesia were compared between the two groups.
The patients and controls were matched for age, gender, height, weight, and body mass index. No significant difference in the mount of drug administered was found between the test and control groups at 0-24 h after the operation; however, a significant difference was observed at 24-48 h after the operation between the two groups. No difference was found in the postoperative pain score, number of side effects, and patient satisfaction between the two groups.
Patient-controlled anesthesia administered at changing rates of infusion has similar numbers of side effects as infusion performed at a fixed rate; however, the former allows for efficient and safe management of postoperative pain even in small doses.
术后疼痛控制是术后患者管理的一个重要方面。在术后疼痛控制方法中,患者自控镇痛(PCA)是最常用的方法。本研究测试了一种根据时间调整剂量的PCA方法的便利性和安全性。
本研究纳入了100例先前接受过正颌手术、椎间盘切除术或全髋关节置换术且希望通过PCA控制术后疼痛的患者。试验组(n = 50)输液速度随时间变化,而对照组(n = 50)以固定速度给药。比较两组患者视觉模拟量表的疼痛评分、补救性镇痛输注次数、副作用以及患者对镇痛的满意度。
患者和对照组在年龄、性别、身高、体重和体重指数方面相匹配。术后0 - 24小时试验组和对照组给药量无显著差异;然而,术后24 - 48小时两组间观察到显著差异。两组术后疼痛评分、副作用数量和患者满意度无差异。
以变化的输液速度进行患者自控麻醉与以固定速度输液的副作用数量相似;然而,前者即使小剂量也能实现高效且安全的术后疼痛管理。