Caplazi P, Melzer K, Goetzmann R, Rohner-Cotti A, Bracher V, Zlinszky K, Ehrensperger F
Institut für Veterinärpathologie, Universität Zürich.
Schweiz Arch Tierheilkd. 1999;141(11):521-7.
Borna disease (BD) is a rare immunopathological disorder of the central nervous system (CNS) caused by infection with Borna disease virus (BDV) and histologically characterized by mononuclear encephalomyelitis. BD primarily affects equines and sheep in well defined endemic areas of central Europe, but BDV infections have also been reported in other host species including humans, as well as in non endemic regions. In this paper recent data on the pathogenesis of BD are reviewed and the current situation in Switzerland and the Principality of Liechtenstein is summarized.
博尔纳病(BD)是一种由博尔纳病病毒(BDV)感染引起的罕见的中枢神经系统免疫病理疾病,组织学特征为单核细胞性脑脊髓炎。BD主要影响中欧明确的地方性流行地区的马和绵羊,但在包括人类在内的其他宿主物种以及非流行地区也有BDV感染的报道。本文综述了BD发病机制的最新数据,并总结了瑞士和列支敦士登公国的现状。