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结核性腹膜炎:35例分析

Tuberculous peritonitis: analysis of 35 cases.

作者信息

Wang H K, Hsueh P R, Hung C C, Chang S C, Luh K T, Hsieh W C

机构信息

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC.

出版信息

J Microbiol Immunol Infect. 1998 Jun;31(2):113-8.

PMID:10596989
Abstract

Thirty five patients with tuberculous peritonitis were studied retrospectively. Tuberculous peritonitis was defined as the isolation of Mycobacterium tuberculosis from ascites or dialysate, and/or caseating granuloma/acid-fast bacilli from peritoneal biopsy specimens from patients with pulmonary tuberculosis or a response to treatment for tuberculosis. Among the patients studied, nine with cirrhosis of the liver; seven with diabetes mellitus and six with end-stage renal disease, of whom four had undergone continuous ambulatory peritoneal dialysis. The most frequent signs of tuberculous peritonitis included ascites, fever and anemia. Ascites was found in 31 patients (89%). Abnormal findings on chest radiographs were found in 26 patients (74%), of whom 22 patients (63%) had pleural effusion and five had miliary lung lesions. Seven out of 35 patients were found to have positive culture of sputum or pleural effusion for M. tuberculosis. Two patients were found to have concomitant tuberculous peritonitis and enteritis. Multiple organ involvement was found in eight patients. Eleven patients (31%) died: eight were older than 60 years; six had cirrhosis of the liver and nine were diagnosed post-mortemly. In Taiwan, tuberculous peritonitis should be considered in patients with abnormality of chest radiography and nonresolving peritonitis.

摘要

对35例结核性腹膜炎患者进行了回顾性研究。结核性腹膜炎的定义为从腹水或透析液中分离出结核分枝杆菌,和/或从肺结核患者的腹膜活检标本中发现干酪样肉芽肿/抗酸杆菌,及/或对结核病治疗有反应。在所研究的患者中,9例患有肝硬化;7例患有糖尿病,6例患有终末期肾病,其中4例接受了持续性非卧床腹膜透析。结核性腹膜炎最常见的体征包括腹水、发热和贫血。31例患者(89%)出现腹水。26例患者(74%)胸部X线片有异常表现,其中22例患者(63%)有胸腔积液,5例有粟粒性肺病变。35例患者中有7例痰或胸腔积液结核分枝杆菌培养呈阳性。发现2例患者同时患有结核性腹膜炎和肠炎。8例患者有多器官受累。11例患者(31%)死亡:8例年龄大于60岁;6例患有肝硬化,9例为尸检确诊。在台湾,胸部X线片异常且腹膜炎不缓解的患者应考虑结核性腹膜炎。

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