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儿童结核性腹膜炎:9例报告及文献复习

Tuberculous peritonitis in children: report of nine patients and review of the literature.

作者信息

Dinler Gönül, Sensoy Gülnar, Helek Deniz, Kalayci Ayhan Gazi

机构信息

Division of Gastroenterology, Hepatology and Nutrition, Ondokuz Mayis University Hospital, Kurupelit, Samsun, 55139, Turkey.

出版信息

World J Gastroenterol. 2008 Dec 21;14(47):7235-9. doi: 10.3748/wjg.14.7235.

Abstract

AIM

To present our experience with tuberculous peritonitis treated in our hospital from 2002-2007.

METHODS

We reviewed the medical records of 9 children with tuberculous peritonitis.

RESULTS

Nine patients (5 boys, 4 girls) of mean age 14.2 years were diagnosed with peritoneal tuberculosis. All patients presented with abdominal distention. Abdominal pain was seen in 55.5% and fever in 44.4% of the patients. Four cases had coexisting pleural effusion and two had pulmonary tuberculosis with parenchymal consolidation. Ultrasonography found ascites with septation in 7 patients. Two patients had only ascites without septation. Ascitic fluid analysis of 8 patients yielded serum-ascite albumin gradients of less than 1.1 gr/dL. Laparoscopy and laparotomy showed that whitish tuberculi were the most common appearance. Adhesions were also seen in three cases. The diagnosis of peritoneal tuberculosis was confirmed histo-pathologically in 7 patients and microbiologically in two. Two patients had been diagnosed by ascitic fluid diagnostic features and a positive response to antituberculous treatment. All patients completed the antituberculous therapy without any complications.

CONCLUSION

Tuberculous peritonitis has to be clinically suspected in all patients with slowly progressive abdominal distension, particularly when it is accompanied by fever and pain. Laparoscopy and peritoneal biopsy are still the most reliable, quick and safe methods for the diagnosis of tuberculous peritonitis.

摘要

目的

介绍我院2002年至2007年治疗结核性腹膜炎的经验。

方法

我们回顾了9例结核性腹膜炎患儿的病历。

结果

9例患者(5例男孩,4例女孩),平均年龄14.2岁,被诊断为结核性腹膜炎。所有患者均有腹胀表现。55.5%的患者有腹痛,44.4%的患者有发热。4例合并胸腔积液,2例合并肺结核伴实质浸润。超声检查发现7例患者有分隔性腹水。2例患者仅有无分隔的腹水。8例患者的腹水分析显示血清-腹水白蛋白梯度小于1.1g/dL。腹腔镜检查和剖腹手术显示,白色结节是最常见的表现。3例患者还可见粘连。7例患者经组织病理学确诊为结核性腹膜炎,2例经微生物学确诊。2例患者通过腹水诊断特征和抗结核治疗的阳性反应确诊。所有患者均完成抗结核治疗,无任何并发症。

结论

对于所有缓慢进展性腹胀的患者,尤其是伴有发热和疼痛时,临床上必须怀疑结核性腹膜炎。腹腔镜检查和腹膜活检仍然是诊断结核性腹膜炎最可靠、快速和安全的方法。

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