Labbé D, Badie Modiri B, Petit F
CHU de Caen.
Rev Stomatol Chir Maxillofac. 1999 Oct;100(4):175-9.
The analysis of 62 cases of nevus sebaceus of Jadassohn and the study of the literature allows to define the clinical and histo-pathologic features of this benign tumor. The massive development of sebaceous glands, papillomatous epidermal hyperplasia, and maturation of apocrines glands, are present in a considerable number of cases. The lesions occurred on the scalp, face, auricular area and neck and are usually present at birth as a yellowish orange area. At puberty, the lesion becomes yellow to dark-brown and is verrucoid and micronodular. Almost all are hair-deficit nevi, and the final stage is the development of secondary tumors of the skin within the lesion. The risk of degeneration in basal-cell carcinoma justifies systematic surgical treatment.
对62例 Jadassohn皮脂腺痣的分析以及文献研究,有助于明确这种良性肿瘤的临床和组织病理学特征。相当多病例中存在皮脂腺的大量增生、乳头瘤样表皮增生以及顶泌汗腺成熟。病变发生于头皮、面部、耳部区域和颈部,通常在出生时表现为淡黄色橙色区域。青春期时,病变变为黄色至深褐色,呈疣状和微结节状。几乎所有都是无毛痣,最终阶段是病变内皮肤继发肿瘤的发生。基底细胞癌退变的风险使得系统性手术治疗成为必要。