Krajnc I
Department Of Internal Medicine, Rheumatology, Teaching Hospital Maribor, Ljubljanska, Slovenia.
Adv Exp Med Biol. 1999;455:181-6.
In diseases of an unknown etiology, such as the idiopathic inflammatory myopathies, we must tackle first of all the question of classification and the degree of disease activity before we can institute treatment. The majority of idiopathic inflammatory myopathies are diagnosed clinically and confirmed by biopsy. The presently applicable methods of diagnosis and evaluation of idiopathic inflammatory myopathy have certain limitations, and hence it is necessary to apply new methods of rating the disease activities. Magnetic resonance imaging (MRI) and 99m-technetium muscle-scanning are the latest noninvasive methods for evaluation of disease activities with myositis. Future laboratory methods to determine the numerous myositis-specific autoantibodies will probably enable identification of subsets of these diseases.
在病因不明的疾病中，如特发性炎性肌病，在开始治疗之前，我们必须首先解决分类问题和疾病活动程度问题。大多数特发性炎性肌病通过临床诊断并经活检证实。目前用于诊断和评估特发性炎性肌病的方法有一定局限性，因此有必要应用新的疾病活动度评估方法。磁共振成像（MRI）和锝-99m肌肉扫描是评估肌炎疾病活动度的最新无创方法。未来用于检测众多肌炎特异性自身抗体的实验室方法可能会有助于识别这些疾病的亚型。
