Del Grande Filippo, Carrino John A, Del Grande Maria, Mammen Andrew L, Christopher Stine Lisa
Russell H. Morgan Department of Radiology and Radiological Science, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.
Top Magn Reson Imaging. 2011 Apr;22(2):39-43. doi: 10.1097/RMR.0b013e31825b2c35.
The following article reviews the role of magnetic resonance imaging (MRI) in patients with idiopathic inflammatory myopathies (IIMs), focusing on the 3 major types of IIM: polymyositis, dermatomyositis, and inclusion-body myositis. After a brief introduction with general information about IIM, we will discuss the reasons why MRI plays an important role in the diagnosis and management of patients with polymyositis, dermatomyositis, and inclusion-body myositis. Magnetic resonance imaging can confirm the diagnosis and can help to phenotype the disease. Moreover, the support of MRI is important in addressing the muscle biopsy site and in reducing the high false-negative rate of biopsy when performed in a blind fashion. In monitoring therapy, MRI can add important information about the activity of the muscle disease and can identify cases where continued immunosuppressive therapy is no longer warranted owing to complete fatty replacement of the muscles. Lastly, we provide an overview about some advanced MRI techniques that focus more on function than on morphology of muscle.
以下文章综述了磁共振成像（MRI）在特发性炎性肌病（IIM）患者中的作用，重点关注IIM的3种主要类型：多发性肌炎、皮肌炎和包涵体肌炎。在简要介绍IIM的一般信息后，我们将讨论MRI在多发性肌炎、皮肌炎和包涵体肌炎患者的诊断和管理中发挥重要作用的原因。磁共振成像可以确诊疾病，并有助于对疾病进行分型。此外，MRI的支持对于确定肌肉活检部位以及减少盲目进行活检时的高假阴性率很重要。在监测治疗时，MRI可以提供有关肌肉疾病活动的重要信息，并可以识别由于肌肉完全脂肪替代而不再需要继续进行免疫抑制治疗的病例。最后，我们概述了一些更关注肌肉功能而非形态的先进MRI技术。
