Jensen R B, Shapiro L
Department of Developmental Biology, Stanford University School of Medicine, Beckman Center B300, Stanford, CA 94305-5329, USA.
Curr Opin Cell Biol. 1999 Dec;11(6):726-31. doi: 10.1016/s0955-0674(99)00043-5.
Recent work has dramatically changed our view of chromosome segregation in bacteria. Rather than being a passive process, it involves rapid movement of parts of the circular chromosome. Several genes involved in chromosome segregation have been identified, and the analysis of their functions and intracellular localization are beginning to shed light on the mechanisms that ensure efficient chromosome segregation.
近期的研究工作极大地改变了我们对细菌中染色体分离的看法。它并非是一个被动过程,而是涉及环状染色体部分区域的快速移动。已鉴定出几个参与染色体分离的基因,对其功能和细胞内定位的分析开始揭示确保有效染色体分离的机制。