快速生长分枝杆菌对泰利霉素（HMR 3647）及其他七种抗菌药物的体外敏感性
In vitro susceptibilities of rapidly growing mycobacteria to telithromycin (HMR 3647) and seven other antimicrobials.
作者信息
Fernández-Roblas R, Esteban J, Cabria F, López J C, Jiménez M S, Soriano F
机构信息
Department of Medical Microbiology, Fundación Jiménez Díaz, Madrid, Spain.
出版信息
Antimicrob Agents Chemother. 2000 Jan;44(1):181-2. doi: 10.1128/AAC.44.1.181-182.2000.
Abstract
The antimicrobial activities of telithromycin (HMR 3647) and seven other antimicrobials against 94 strains of rapidly growing mycobacteria were determined. Telithromycin at a concentration of 1 microg/ml inhibited Mycobacterium peregrinum (100%), Mycobacterium chelonae (80%), Mycobacterium abscessus-Mycobacterium mucogenicum (44.4%), and Mycobacterium fortuitum (2.1%). All or most strains of M. peregrinum, M. fortuitum, and M. mucogenicum were inhibited by 2 microg of quinolones per ml.
摘要
测定了泰利霉素（HMR 3647）及其他7种抗菌药物对94株快速生长分枝杆菌的抗菌活性。浓度为1微克/毫升的泰利霉素可抑制100%的偶发分枝杆菌、80%的龟分枝杆菌、44.4%的脓肿分枝杆菌-产黏液分枝杆菌及2.1%的偶然分枝杆菌。每毫升2微克的喹诺酮类药物可抑制所有或大多数偶发分枝杆菌、偶然分枝杆菌及产黏液分枝杆菌菌株。
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