儿童及青少年狼疮性肾炎中的远端肾小管功能障碍。

Distal tubular dysfunction in lupus nephritis of childhood and adolescence.

作者信息

Hataya H, Ikeda M, Ide Y, Kobayashi Y, Kuramochi S, Awazu M

机构信息

Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan.

出版信息

Pediatr Nephrol. 1999 Nov;13(9):846-9. doi: 10.1007/s004670050713.

DOI:10.1007/s004670050713

PMID:10603134

Abstract

We describe a girl with lupus nephritis who presented with distal renal tubular acidosis and hyporeninemic hypoaldosteronism. While distal tubular dysfunction is well recognized in adult systemic lupus erythematosus (SLE), only a few pediatric patients have been reported. Evaluation of five pediatric patients with SLE revealed that distal tubular dysfunction in childhood and adolescence is rare.

摘要

我们描述了一名患有狼疮性肾炎的女孩，她出现了远端肾小管酸中毒和低肾素性低醛固酮血症。虽然远端肾小管功能障碍在成人系统性红斑狼疮（SLE）中已得到充分认识，但仅有少数儿科患者的相关报道。对五名患有SLE的儿科患者的评估显示，儿童和青少年期的远端肾小管功能障碍较为罕见。