Kozeny G A, Hurley R M, Fresco R, Vertuno L L, Bansal V K, Hano J E
Am J Nephrol. 1986;6(4):321-4. doi: 10.1159/000167183.
Hyperkalemia has been noted to occur spontaneously in patients with long-standing systemic lupus erythematosus who did not have advanced renal insufficiency. The patients previously described all had relatively normal renin-aldosterone systems, and the hyperkalemia was thus presumed to be secondary to a primary defect in renal tubular potassium secretion. We describe at 10-year-old girl with lupus nephritis, without significant renal insufficiency, who had hyperkalemia from hyporeninemic hypoaldosteronism postulated to be due to vasculitis involving the afferent/efferent arterioles and juxtaglomerular apparatus.
在没有晚期肾功能不全的长期系统性红斑狼疮患者中，已注意到会自发发生高钾血症。先前描述的患者肾素 - 醛固酮系统相对正常，因此推测高钾血症继发于肾小管钾分泌的原发性缺陷。我们描述了一名10岁患狼疮性肾炎的女孩，她没有明显的肾功能不全，其高钾血症是由低肾素性低醛固酮血症引起的，推测这是由于累及入球/出球小动脉和球旁器的血管炎所致。
