Gislason T, Janson C, Tómasson K
Department of Pulmonary Medicine, Vífilsstadir, Iceland.
J Sleep Res. 1995 Jun;4(S1):145-149. doi: 10.1111/j.1365-2869.1995.tb00204.x.
Previous studies have reported a great difference in snoring prevalence in different populations. In a recent study on men and women 20-45 y old, living in Sweden (Uppsala, Gothenbourg), Iceland (Reykjavík) and Belgium (Antwerp), data concerning snoring, etc., were collected using the same questions and scales in all the countries. In all four areas the prevalence of snoring was the same: 5% of men and 2-3% of women reported snoring every night. In all areas snoring was positively correlated with age, male sex and body mass index. It was therefore assumed that the previous difference in snoring prevalence is probably an artifact of different methodologies. The connection between snoring and systemic hypertension has been much disputed during the last decade. The high prevalence of hypertension in the sleep apnoea syndrome has been explained by obesity/age/male gender/sleep apnoea and/or snoring. In one recent study snoring did not contribute independently to the prediction of hypertension, while other studies indicate that snoring is an independent risk factor for hypertension. After reviewing some of the epidemiological literature it was found that these studies are bound to identify almost entirely different subgroups of the population as snorers since the prevalence of snoring is rated on different types of frequency scales with words like 'never', 'often' or the number of nights per week. The questions used are also different. In general it can be stated that the smaller the proportion of the population identified as snorers the more often there is a statistically significant association with hypertension. The relationship between snoring and hypertension is considered to be unclear due to the different research methods used, and to the uncertain role played by confounding factors such as obesity. There is a need for population-based, prospective, studies with more uniform definitions of the term 'snoring' based on objective measurements of upper airway resistance during sleep, together with haemodynamic studies.
以往的研究报告了不同人群中打鼾患病率的巨大差异。在最近一项针对年龄在20 - 45岁之间、生活在瑞典(乌普萨拉、哥德堡)、冰岛(雷克雅未克)和比利时(安特卫普)的男性和女性的研究中,所有国家都使用相同的问题和量表收集了有关打鼾等的数据。在所有这四个地区,打鼾的患病率是相同的:5%的男性和2 - 3%的女性报告每晚打鼾。在所有地区,打鼾都与年龄、男性性别和体重指数呈正相关。因此可以推测,以前打鼾患病率的差异可能是不同方法造成的假象。在过去十年中,打鼾与系统性高血压之间的联系一直备受争议。睡眠呼吸暂停综合征中高血压的高患病率已被解释为肥胖/年龄/男性性别/睡眠呼吸暂停和/或打鼾所致。在最近的一项研究中,打鼾并非独立地有助于预测高血压,而其他研究表明打鼾是高血压的独立危险因素。在回顾了一些流行病学文献后发现,由于打鼾患病率是根据不同类型的频率量表(如“从不”“经常”或每周的夜晚次数)来评定的,这些研究几乎必然会将完全不同的人群亚组识别为打鼾者。所使用的问题也各不相同。一般来说,可以说被识别为打鼾者的人群比例越小,与高血压之间存在统计学显著关联的情况就越常见。由于所采用的研究方法不同,以及肥胖等混杂因素所起的作用不确定,打鼾与高血压之间的关系被认为尚不明确。有必要进行基于人群的前瞻性研究,对“打鼾”一词采用更统一的定义,该定义基于睡眠期间上气道阻力的客观测量,同时进行血流动力学研究。