Smit A F
Axys Pharmaceuticals, Inc., La Jolla, 92037-1029, USA.
Curr Opin Genet Dev. 1999 Dec;9(6):657-63. doi: 10.1016/s0959-437x(99)00031-3.
The bulk of the human genome is ultimately derived from transposable elements. Observations in the past year lead to some new and surprising ideas on functions and consequences of these elements and their remnants in our genome. The many new examples of human genes derived from single transposon insertions highlight the large contribution of selfish DNA to genomic evolution.
人类基因组的大部分最终源自转座元件。过去一年的观察结果引发了一些关于这些元件及其在我们基因组中的残余物的功能和影响的新的、令人惊讶的观点。许多源自单个转座子插入的人类基因的新例子突出了自私DNA对基因组进化的巨大贡献。