Chowdhury I, Chatterjee B
Division of Palynology and Environmental Biology, Department of Botany, Bose Institute, 93/1 Acharya P.C. Road, Calcutta - 700 009, India.
Ann Agric Environ Med. 1999;6(2):91-7.
A group of 48 patients with asthma and rhinitis, sensitive to house dust allergen, underwent immunotherapy with an extract of crude house dust for a period of 6-12 months. The clinical results of the therapy, as evaluated by symptom medication scores, demonstrated the significant clinical improvement of the patients treated by crude dust extract (CDE) compared to those treated by placebo. A significant (p < 0.001) reduction of specific IgE and elevation (p < 0.001) of specific IgG in the post-therapeutic patient sera was demonstrated by serological tests. A good correlation was observed between the changes in specific IgE and IgG levels.
一组48名对屋尘过敏原敏感的哮喘和鼻炎患者接受了粗屋尘提取物免疫治疗，为期6至12个月。通过症状药物评分评估的治疗临床结果表明，与接受安慰剂治疗的患者相比，接受粗尘提取物（CDE）治疗的患者临床症状有显著改善。血清学检测显示，治疗后患者血清中特异性IgE显著降低（p < 0.001），特异性IgG升高（p < 0.001）。特异性IgE和IgG水平的变化之间观察到良好的相关性。
