Jeffcott L B
J Reprod Fertil Suppl. 1975 Oct(23):727-33.
The mechanism of transfer of maternal immunity to the foal is reviewed. Maximal efficiency of macromolecular absorption by specialized cells of the small intestine exists soon after birth. The absorptive cells are progressively replaced by more mature-looking cells incapable of taking up large molecules and the rate of absorption is reduced in a linear decline and ceases completely within 24 hr. Passive antibody levels fall rapidly in the first 4 weeks of life to less than half their original values and have usually completely disappeared by 6 months of age. The foal shows immunological competence soon after birth although appreciable levels of autogenous immunoglobulins are not usually attained until 2 to 3 months of age.
本文综述了母源免疫传递给幼驹的机制。出生后不久，小肠特化细胞对大分子的吸收效率达到最高。吸收细胞逐渐被看起来更成熟、无法摄取大分子的细胞所取代，吸收速率呈线性下降，在24小时内完全停止。被动抗体水平在出生后的前4周迅速下降至不到其初始值的一半，通常在6月龄时完全消失。幼驹在出生后不久就表现出免疫能力，尽管自体免疫球蛋白的可观水平通常要到2至3月龄时才能达到。
