Ott G, Becker W
Langenbecks Arch Chir. 1975 Nov;339:305-13. doi: 10.1007/BF01257522.
Complete documentation of the pathological spectrum of a great many similar cancer patients requires interdisciplinary coordination and the absence of ambition of any particular branch. The application of a TNM system devised by the authors for the classification of skeletal neoplasms showed in a retrospective study of 600 cases that the degree of infiltration into the periosteum and soft tissue, which opens more lymphatics to metastasizing tumor cells, is a more relevant parameter of the TNM system than the size of the tumor itself.
全面记录大量相似癌症患者的病理谱需要多学科协作,且任何特定学科都不能有野心。作者设计的用于骨骼肿瘤分类的TNM系统在一项对600例病例的回顾性研究中显示,肿瘤向骨膜和软组织的浸润程度比肿瘤本身的大小更能反映TNM系统的相关参数,因为这种浸润会为转移的肿瘤细胞打开更多淋巴管。