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光治疗性角膜切削术治疗复发性角膜糜烂。

Phototherapeutic keratectomy for treatment of recurrent corneal erosion.

作者信息

Jain S, Austin D J

机构信息

Eye Department, Leicester Royal Infirmary, England.

出版信息

J Cataract Refract Surg. 1999 Dec;25(12):1610-4. doi: 10.1016/s0886-3350(99)00262-x.

Abstract

PURPOSE

To study the role of phototherapeutic keratectomy (PTK) in the management of recurrent corneal erosion (RCE) refractory to other forms of treatment.

SETTING

The Eye Department of Leicester Royal Infirmary, a tertiary referral center, Leicester, England.

METHOD

A retrospective analysis of all patients who had PTK for refractory RCE between July 1994 and October 1998 was performed. The patients were recalled to determine whether they had further symptoms and whether there had been a change in their refractive error or their best corrected visual acuity.

RESULTS

Seventy-seven eyes of 68 patients were treated and divided into 3 etiologic groups: trauma, 40 eyes; corneal dystrophy, 24 eyes; and no established cause (idiopathic), 13 eyes. Phototherapeutic keratectomy was combined with photorefractive keratectomy (PRK) in 6 eyes with a good result. A single treatment was performed in 71 eyes (92.2%). No significant refractive change occurred in 67.5% of eyes; 22.1% developed hyperopia (range 0 to +2.0 diopters [D]), and 10.3% developed myopia (range 0 to -1.5 D). Best corrected visual acuity was unchanged in 72.7% of eyes; 11.7% lost 1 Snellen line and 15.5% gained 1 line. There were no symptoms in 68.8% of eyes; in 31.2%, minor symptoms were noted in the morning, and these patients continued to use ocular lubricants at night.

CONCLUSION

Phototherapeutic keratectomy is a safe and effective treatment for refractory RCE and, where appropriate, can be combined with PRK.

摘要

目的

研究光治疗性角膜切削术(PTK)在治疗对其他治疗方法无效的复发性角膜糜烂(RCE)中的作用。

背景

英国莱斯特皇家医院眼科,一家三级转诊中心,位于莱斯特。

方法

对1994年7月至1998年10月间接受PTK治疗难治性RCE的所有患者进行回顾性分析。召回患者以确定他们是否有进一步的症状,以及屈光不正或最佳矫正视力是否有变化。

结果

68例患者的77只眼接受了治疗,分为3个病因组:外伤,40只眼;角膜营养不良,24只眼;病因不明(特发性),13只眼。6只眼将光治疗性角膜切削术与准分子激光角膜切削术(PRK)联合应用,效果良好。71只眼(92.2%)进行了单次治疗。67.5%的眼屈光无明显变化;22.1%出现远视(范围0至+2.0屈光度[D]),10.3%出现近视(范围0至-1.5 D)。72.7%的眼最佳矫正视力无变化;11.7%下降1行Snellen视力表,15.5%提高1行。68.8%的眼无症状;31.2%的眼在早晨有轻微症状,这些患者夜间继续使用眼部润滑剂。

结论

光治疗性角膜切削术是治疗难治性RCE的一种安全有效的方法,在适当情况下可与PRK联合应用。

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