Kremer Israel
Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tikva Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv - Israel.
Eur J Ophthalmol. 2012;22 Suppl 7:S120-5. doi: 10.5301/ejo.5000097.
To report on phototherapeutic keratectomy (PTK) in myopic patients who developed spontaneous recurrent corneal erosions (RCE) following IntraLASIK.
Recurrent corneal erosions developed spontaneously 3-6 months following IntraLASIK in 4 eyes of 4 myopic patients. Diffuse lamellar keratitis (DLK) subsequently developed. Initially, all patients underwent mechanical scraping of the loose epithelium. The erosion healed but recurred after 2-4 months. Phototherapeutic keratectomy was performed following scraping of the whole loose flap epithelium. The ablation diameter was 6.5 mm, transition zone was 2.7 mm, and the depth was 12 µm. This program was followed by a refractive laser treatment to correct +0.75 diopter at a zone of 6.0-9.0 mm.
Recurrent corneal erosions healed completely following PTK within 8-10 days and DLK disappeared gradually within 9-12 days. Steroid drops were continued for 6-10 weeks according to degree of stromal haze. Final refraction revealed no significant change. Visual rehabilitation was noted to be slow. No patient lost best-corrected visual acuity. A +1-degree reticular haze was noted in all patients 4.5 years following treatment. The patients remained asymptomatic and corneal erosion did not recur during the follow-up period.
Phototherapeutic keratectomy was found to be an effective treatment for late spontaneous RCE after IntraLASIK and prevented recurrences. A mild stromal haze remained after laser treatment without loss of best-corrected visual acuity.
报告准分子激光原位角膜磨镶术(IntraLASIK)后发生自发性复发性角膜糜烂(RCE)的近视患者接受光治疗性角膜切削术(PTK)的情况。
4例近视患者的4只眼在IntraLASIK术后3 - 6个月自发出现复发性角膜糜烂。随后发生了弥漫性板层角膜炎(DLK)。最初,所有患者均接受了松动上皮的机械刮除。糜烂愈合,但在2 - 4个月后复发。在刮除整个松动瓣上皮后进行了光治疗性角膜切削术。消融直径为6.5毫米,过渡区为2.7毫米,深度为12微米。此程序之后进行屈光性激光治疗,以在6.0 - 9.0毫米区域矫正+0.75屈光度。
PTK后复发性角膜糜烂在8 - 10天内完全愈合,DLK在9 - 12天内逐渐消失。根据基质混浊程度,继续使用类固醇滴眼液6 - 10周。最终验光显示无显著变化。视力恢复较慢。没有患者丧失最佳矫正视力。治疗后4.5年,所有患者均出现+1度的网状混浊。患者在随访期间无症状,角膜糜烂未复发。
发现光治疗性角膜切削术是IntraLASIK术后晚期自发性RCE的有效治疗方法,并可防止复发。激光治疗后残留轻度基质混浊,但未丧失最佳矫正视力。