Autrata Rudolf, Rehurek Jaroslav, Vodicková Kristina
Department of Ophthalmology, Masaryk University Hospital, Brno 61300, Czech Republic.
J Cataract Refract Surg. 2004 Sep;30(9):1909-16. doi: 10.1016/j.jcrs.2004.02.047.
To evaluate the efficacy and safety of phototherapeutic keratectomy (PTK) for the treatment of superficial corneal opacities, surface irregularities, epithelial instability, and reepithelialization failure in pediatric patients and study the visual and refractive changes after combined PTK and photorefractive keratectomy (PRK).
Department of Ophthalmology, Masaryk University Hospital, Brno, Czech Republic.
This retrospective clinical study comprised children who had PTK or PTK combined with PRK from September 1996 to January 2000. The goals of treatment were to improve visual acuity and reduce or eliminate subjective ocular discomfort (eg, pain, lacrimation, and photophobia). A Nidek EC-5000 excimer laser was used in PTK mode with a 3.0 to 6.0 mm optical zone and a 4.0 to 7.5 mm transition zone.
Forty-one pediatric patients (41 eyes) were included. Twenty-three eyes had PTK only, and 18 eyes had PTK combined with PRK to reduce preoperative myopia (11 eyes) or hyperopia (7 eyes). The mean patient age was 11.4 years (range 8 to 18 years) and the mean follow-up, 4.8 years (range 3 to 6 years). The best spectacle-corrected visual acuity (BSCVA) improved in all patients, and episodes of ocular pain or discomfort, lacrimation, and photophobia diminished. The mean preoperative BSCVA of 6/38 (range 6/10 to 1/60) improved to 6/12 (range 6/6 to 6/38) at the last postoperative examination. Eight eyes gained 5 or more Snellen lines of BSCVA; 11 gained 4 lines, 9 gained 3 lines, 7 gained 2 lines, 5 gained 1 line, and 1 eye was unchanged. No eye lost a line of BSCVA. The mean preoperative spherical equivalent (SE) decreased from -5.32 to -1.16 diopters (D) in the 11 myopic eyes and from +4.72 to +1.51 D in the 7 hyperopic eyes within 3 years of the combined procedure.
Phototerapeutic keratectomy is an effective and safe procedure for the treatment of various surface corneal disorders in children. It can improve best corrected visual acuity and eliminate ocular pain and irritation. Preoperative myopia and hyperopia were effectively reduced by a combination of PTK and PRK.
评估光治疗性角膜切削术(PTK)治疗小儿患者浅表角膜混浊、表面不规则、上皮不稳定及上皮化失败的疗效和安全性,并研究PTK联合准分子激光角膜切削术(PRK)后的视力和屈光变化。
捷克共和国布尔诺马萨里克大学医院眼科。
这项回顾性临床研究纳入了1996年9月至2000年1月接受PTK或PTK联合PRK治疗的儿童。治疗目标是提高视力并减轻或消除主观眼部不适(如疼痛、流泪和畏光)。使用Nidek EC - 5000准分子激光,采用PTK模式,光学区为3.0至6.0 mm,过渡区为4.0至7.5 mm。
纳入41例小儿患者(41只眼)。23只眼仅接受PTK治疗,18只眼接受PTK联合PRK治疗以降低术前近视(11只眼)或远视(7只眼)。患者平均年龄为11.4岁(范围8至18岁),平均随访时间为4.8年(范围3至6年)。所有患者的最佳矫正视力(BSCVA)均有提高,眼部疼痛或不适、流泪及畏光发作减少。术后最后一次检查时,术前平均BSCVA为6/38(范围6/10至1/60)提高到了6/12(范围6/6至6/38)。8只眼的BSCVA提高了5行或更多;11只眼提高了4行,9只眼提高了3行,7只眼提高了2行,5只眼提高了1行,1只眼无变化。没有眼的BSCVA下降一行。联合手术3年内,11只近视眼中术前平均球镜当量(SE)从-5.32屈光度(D)降至-1.16 D,7只远视眼中从+4.72 D降至+1.51 D。
光治疗性角膜切削术是治疗儿童各种角膜表面疾病的有效且安全的方法。它可提高最佳矫正视力并消除眼部疼痛和刺激。PTK与PRK联合可有效降低术前近视和远视。