拟南芥RTM1基因的克隆，该基因控制烟草蚀纹病毒长距离移动的限制。
Cloning of the Arabidopsis RTM1 gene, which controls restriction of long-distance movement of tobacco etch virus.
作者信息
Chisholm S T, Mahajan S K, Whitham S A, Yamamoto M L, Carrington J C
机构信息
Institute of Biological Chemistry, Washington State University, Pullman, WA 99164-6340, USA.
出版信息
Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):489-94. doi: 10.1073/pnas.97.1.489.
Abstract
The locus RTM1 is necessary for restriction of long-distance movement of tobacco etch virus in Arabidopsis thaliana without causing a hypersensitive response or inducing systemic acquired resistance. The RTM1 gene was isolated by map-based cloning. The deduced gene product is similar to the alpha-chain of the Artocarpus integrifolia lectin, jacalin, and to several proteins that contain multiple repeats of a jacalin-like sequence. These proteins comprise a family with members containing modular organizations of one or more jacalin repeat units and are implicated in defense against viruses, fungi, and insects.
摘要
位点RTM1对于限制烟草蚀纹病毒在拟南芥中的长距离移动是必需的，且不会引起过敏反应或诱导系统获得性抗性。RTM1基因通过图位克隆法分离得到。推导的基因产物与面包树凝集素jacalin的α链以及几种含有多个jacalin样序列重复的蛋白质相似。这些蛋白质构成了一个家族，其成员包含一个或多个jacalin重复单元的模块化结构，并且与抵御病毒、真菌和昆虫有关。
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