Tomich C E, Moll M C
J Oral Surg. 1976 Mar;34(3):265-8.
A case of palisaded, encapsulated neuroma of the lower lip has been presented. To the best of our knowledge, this is the first reported instance in the dental literature. The lesion characteristically occurs on the skin of the face near the oral, nasal, and orbital mucocutaneous junctions and, therefore, is readily visible to the oral diagnostician. It occurs most often in middle-aged individuals and, although it may clinically mimic other lesions, the operative finding of an easily enucleated mass near a mucocutaneous junction should suggest this lesion in the differential diagnosis. Histologically, the lesion is characterized by three distinct zones--an outer compressed fibrous connective tissue capsule, an inner myxomatous zone, and a central zone of proliferating Schwann's cells arranged in interlacing fascicles with areas of palisaded cells and organoid structures. The lesion is treated by enucleation or excision and has no tendency to recur.
本文报告了一例下唇栅栏状、包膜性神经瘤。据我们所知，这是牙科文献中首次报道的病例。该病变特征性地发生在口腔、鼻腔和眼眶粘膜皮肤交界处附近的面部皮肤上，因此口腔诊断医生很容易看到。它最常发生在中年个体中，尽管在临床上可能与其他病变相似，但在粘膜皮肤交界处附近易于摘除的肿块的手术发现应在鉴别诊断中提示该病变。组织学上，该病变的特征是有三个不同的区域——外层受压的纤维结缔组织包膜、内层粘液瘤样区域以及中央增殖的施万细胞区域，这些细胞排列成交错的束状，有栅栏状细胞区域和类器官结构。该病变通过摘除或切除进行治疗，且无复发倾向。
