Tandon N, Chopra R, Ghoshal S, Singh P, Sharma B S
Departments of Radiotherapy and Oncology, Neurosurgery and Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Neurol India. 1999 Dec;47(4):321-3.
An intracranial mixed germ cell tumour with germinoma and teratoma components is reported. The patient presented with parinaud's syndrome and precocious puberty. The treatment involved partial surgical debulking followed by whole brain radiotherapy (4500 cGY in 25 fraction over 5 weeks) and chemotherapy (consisting of cisplatin and etoposide). Post treatment MRI showed no residual lesion. The controversies in the management are discussed.
报告了一例具有生殖细胞瘤和畸胎瘤成分的颅内混合性生殖细胞肿瘤。患者表现为帕里诺德综合征和性早熟。治疗包括部分手术减瘤,随后进行全脑放疗(5周内25次分割,共4500 cGY)和化疗(由顺铂和依托泊苷组成)。治疗后MRI显示无残留病变。讨论了治疗中的争议。