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一名患无性细胞瘤的患者出现了帕里诺德“加”综合征。

Parinaud «plus» syndrome in a patient with dysgerminoma.

作者信息

Burgueño-Montañés C, Santalla-Castro C, Peña-Suárez J

机构信息

Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

出版信息

Arch Soc Esp Oftalmol. 2016 Jul;91(7):341-5. doi: 10.1016/j.oftal.2016.01.003. Epub 2016 Feb 18.

Abstract

CLINICAL CASE

A 33-year-old male diagnosed with Parinaud's syndrome, exotropia and post-papillary oedema optic atrophy in his left eye. A pineal germinoma was diagnosed after performing neuroimaging scans and a stereotactic biopsy. He was treated with chemotherapy and radiotherapy, showing a complete pathological response. The Parinaud's syndrome persists one year after diagnosis and the patient has refused to have strabismus surgery.

DISCUSSION

Parinaud's syndrome consists of a supranuclear vertical gaze palsy resulting from damage to the midbrain tectum. The involvement of adjacent structures leads to the «Parinaud-plus» syndrome. When a Parinaud's syndrome is accompanied by diplopia («Parinaud-plus» syndrome), extension of the injury into adjacent areas must be considered.

摘要

临床病例

一名33岁男性,被诊断为帕里诺德综合征、外斜视和左眼乳头后水肿性视神经萎缩。经神经影像学扫描和立体定向活检后诊断为松果体生殖细胞瘤。他接受了化疗和放疗,显示出完全的病理反应。帕里诺德综合征在诊断后持续一年,患者拒绝接受斜视手术。

讨论

帕里诺德综合征由中脑顶盖受损导致的核上性垂直凝视麻痹组成。相邻结构的受累导致“帕里诺德加”综合征。当帕里诺德综合征伴有复视(“帕里诺德加”综合征)时,必须考虑损伤扩展到相邻区域。

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