Burgueño-Montañés C, Santalla-Castro C, Peña-Suárez J
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Arch Soc Esp Oftalmol. 2016 Jul;91(7):341-5. doi: 10.1016/j.oftal.2016.01.003. Epub 2016 Feb 18.
A 33-year-old male diagnosed with Parinaud's syndrome, exotropia and post-papillary oedema optic atrophy in his left eye. A pineal germinoma was diagnosed after performing neuroimaging scans and a stereotactic biopsy. He was treated with chemotherapy and radiotherapy, showing a complete pathological response. The Parinaud's syndrome persists one year after diagnosis and the patient has refused to have strabismus surgery.
Parinaud's syndrome consists of a supranuclear vertical gaze palsy resulting from damage to the midbrain tectum. The involvement of adjacent structures leads to the «Parinaud-plus» syndrome. When a Parinaud's syndrome is accompanied by diplopia («Parinaud-plus» syndrome), extension of the injury into adjacent areas must be considered.
一名33岁男性,被诊断为帕里诺德综合征、外斜视和左眼乳头后水肿性视神经萎缩。经神经影像学扫描和立体定向活检后诊断为松果体生殖细胞瘤。他接受了化疗和放疗,显示出完全的病理反应。帕里诺德综合征在诊断后持续一年,患者拒绝接受斜视手术。
帕里诺德综合征由中脑顶盖受损导致的核上性垂直凝视麻痹组成。相邻结构的受累导致“帕里诺德加”综合征。当帕里诺德综合征伴有复视(“帕里诺德加”综合征)时,必须考虑损伤扩展到相邻区域。