Eliashar R, Eliachar I, Gramlich T, Esclamado R, Strome M
Department of Otolaryngology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Otolaryngol Head Neck Surg. 2000 Jan;122(1):84-90. doi: 10.1016/s0194-5998(00)70149-5.
Laryngotracheal stenosis (LTS) is a serious challenge for the otolaryngologist. Although progress has been made in preventing and treating LTS, more research is required. Existing canine models for LTS incur high mortality and morbidity, require relatively complicated procedures or costly equipment, entail lengthy waiting periods, or have unpredictable results. A simple, reliable, and inexpensive procedure, requiring no tracheotomy, is described for creating a canine model for LTS research. The new improved model is compared with previous models described in the literature. It will be especially useful for short-term studies of subglottic or tracheal stenosis.
喉气管狭窄(LTS)对耳鼻喉科医生来说是一项严峻挑战。尽管在预防和治疗LTS方面已取得进展,但仍需要更多研究。现有的LTS犬模型死亡率和发病率高,需要相对复杂的手术或昂贵的设备,等待时间长,或者结果不可预测。本文描述了一种无需气管切开术的简单、可靠且廉价的手术方法,用于创建LTS研究的犬模型。将新的改进模型与文献中描述的先前模型进行比较。它对于声门下或气管狭窄的短期研究将特别有用。