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改良的犬喉气管狭窄模型。

Improved canine model for laryngotracheal stenosis.

作者信息

Eliashar R, Eliachar I, Gramlich T, Esclamado R, Strome M

机构信息

Department of Otolaryngology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

出版信息

Otolaryngol Head Neck Surg. 2000 Jan;122(1):84-90. doi: 10.1016/s0194-5998(00)70149-5.

DOI:10.1016/s0194-5998(00)70149-5
PMID:10629488
Abstract

Laryngotracheal stenosis (LTS) is a serious challenge for the otolaryngologist. Although progress has been made in preventing and treating LTS, more research is required. Existing canine models for LTS incur high mortality and morbidity, require relatively complicated procedures or costly equipment, entail lengthy waiting periods, or have unpredictable results. A simple, reliable, and inexpensive procedure, requiring no tracheotomy, is described for creating a canine model for LTS research. The new improved model is compared with previous models described in the literature. It will be especially useful for short-term studies of subglottic or tracheal stenosis.

摘要

喉气管狭窄(LTS)对耳鼻喉科医生来说是一项严峻挑战。尽管在预防和治疗LTS方面已取得进展,但仍需要更多研究。现有的LTS犬模型死亡率和发病率高,需要相对复杂的手术或昂贵的设备,等待时间长,或者结果不可预测。本文描述了一种无需气管切开术的简单、可靠且廉价的手术方法,用于创建LTS研究的犬模型。将新的改进模型与文献中描述的先前模型进行比较。它对于声门下或气管狭窄的短期研究将特别有用。

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1
Improved canine model for laryngotracheal stenosis.改良的犬喉气管狭窄模型。
Otolaryngol Head Neck Surg. 2000 Jan;122(1):84-90. doi: 10.1016/s0194-5998(00)70149-5.
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[Laryngotracheal stenosis in the adult].[成人喉气管狭窄]
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Subglottic Stenosis.声门下狭窄
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Acute and chronic changes in the subglottis induced by graded carbon dioxide laser injury in the rabbit airway.兔气道内分级二氧化碳激光损伤引起的声门下急性和慢性变化。
Arch Otolaryngol Head Neck Surg. 2008 Jul;134(7):694-702. doi: 10.1001/archotol.134.7.694.
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Electrocautery versus 23% NaOH infiltration to induce subglottic stenosis in a canine experimental model.在犬类实验模型中,电灼术与23%氢氧化钠浸润诱导声门下狭窄的比较。
Pediatr Surg Int. 2007 Dec;23(12):1227-31. doi: 10.1007/s00383-007-2017-4. Epub 2007 Sep 26.