Blickstein I, Goldman R D, Kupferminc M
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel.
Obstet Gynecol. 2000 Jan;95(1):37-42. doi: 10.1016/s0029-7844(99)00474-3.
To assess the risk of vaginal birth of breech first twins by Apgar scores and mortality.
We did a retrospective case-control analysis of data from 13 centers that allow vaginal birth for breech first twins. We used depressed 5-minute Apgar scores and neonatal mortality as main outcome measures between vaginal (n = 239) and cesarean (n = 374) deliveries of pairs with breech first twins, stratified by parity, birth weights of first twins, and types of cesarean. The 95% power of our sample size (alpha = .05) was sensitive enough to detect differences of 5% of the overall sample and 25-30% of subgroups.
Vaginal birth was attempted in 61% of 613 pairs. There were significantly more depressed Apgar scores (P = .008, odds ratio [OR] 2.4, 95% confidence interval [CI] 1.2, 4.7) and neonatal deaths (P < .001, OR 9.5, 95% CI 4.0, 23.4) among vaginal births of pairs in whom first twins weighed less than 1500 g but not among the higher-birth-weight cohort (for depressed Apgar scores: P = .76, OR 1.1, 95% CI 0.6, 2.1). Multiparity and elective cesarean seemed to have little influence on outcome measures. Neonatal mortality was associated with extremely preterm twins.
There was no evidence that vaginal birth is unsafe, in terms of depressed Apgar scores and neonatal mortality, for breech first twins that weighed at least 1500 g.
通过阿氏评分和死亡率评估臀先露双胎经阴道分娩的风险。
我们对13个允许臀先露双胎经阴道分娩的中心的数据进行了回顾性病例对照分析。我们将5分钟阿氏评分低和新生儿死亡率作为主要结局指标,比较臀先露双胎经阴道分娩(n = 239)和剖宫产分娩(n = 374)的情况,并按产次、第一胎儿出生体重和剖宫产类型进行分层。我们样本量的95%效能(α = 0.05)足以检测出占总体样本5%以及亚组25 - 30%的差异。
613对双胎中有61%尝试经阴道分娩。在第一胎儿体重小于1500 g的双胎经阴道分娩中,阿氏评分低的情况(P = 0.008,比值比[OR] 2.4,95%置信区间[CI] 1.2,4.7)和新生儿死亡情况(P < 0.001,OR 9.5,95% CI 4.0,23.4)显著更多,但在出生体重较高的队列中并非如此(阿氏评分低:P = 0.76,OR 1.1,95% CI 0.6,2.1)。经产妇和选择性剖宫产似乎对结局指标影响不大。新生儿死亡率与极早产双胎有关。
就阿氏评分低和新生儿死亡率而言,没有证据表明体重至少1500 g的臀先露双胎经阴道分娩不安全。