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[The protective effect of preliminary adaptation to the stress from disorders of the gas-transport function of the blood in hemorrhagic shock].

作者信息

Arkhipenko Iu V, Zhukova A G, Kizichenko N V, Tarakanov I A, Kozhevnikova L M

出版信息

Patol Fiziol Eksp Ter. 1999 Oct-Dec(4):3-7.

Abstract

To prevent disturbances of blood gas-transport function in hemorrhagic shock, we used cross-over protective effect of adaptation to short-term immobilization stress. Adaptation of rats to stress was associated with a rise in baseline arterial blood, pH in venous blood; fall in PO2, PCO2,P50. Stress-adapted rats appeared more resistant to blood loss. Gas transport 1 hour after hemorrhage was better than in non-adapted animals demonstrated more active compensatory reactions in l low hypoxic damage to the tissues. 2.5-h survival after start of bleeding in control animals made up 35%, in the group of adapted animals--67%. Thus, adaptation to short-term immobilization stress is a non-pharmacological method to prevent hemorrhagic shock.

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