Kasle M J, Klein A I
Oral Surg Oral Med Oral Pathol. 1976 Jun;41(6):789-96. doi: 10.1016/0030-4220(76)90194-8.
Periapical lesions were experimentally induced in forty-five teeth of seven beagle dogs by both septic and aseptic techniques. Preoperative and postoperative serial radiographs were produced with a specifically designed animal head x-ray device, at 30-, 60-, and 90-day periods. Four anatomic study areas, which consisted of the cervical, interradicular, proximal root, and periapical areas of each tooth, were evaluated by viewbox observation of radiographs, television subtraction radiographic imagery, and histologic examination. The findings obtained with the subtracted image and histologic examinations were correlated with viewbox observations. Diagnostic evidence of periapical pathosis was identified in the subtracted image 7 to 42 days before this same evidence was noted on the viewbox radiograph. The periodontal membrane space, lamina dura, bone trabeculae, and medullary spaces were markedly enhanced, with defined outlines of the periapical lesions noted in the subtracted image.
通过感染性和无菌技术,在7只比格犬的45颗牙齿上实验性诱导根尖周病变。使用专门设计的动物头部X射线装置,在术前和术后第30、60和90天拍摄系列X光片。通过观片箱观察X光片、电视减影放射成像和组织学检查,对每个牙齿的四个解剖学研究区域,即颈部、根间、近中牙根和根尖区域进行评估。将减影图像和组织学检查获得的结果与观片箱观察结果进行关联。在观片箱X光片上发现相同证据的7至42天前,在减影图像中就已确定根尖周病变的诊断证据。牙周膜间隙、硬骨板、骨小梁和骨髓腔明显增强,在减影图像中可见根尖周病变的清晰轮廓。