Stimulation of prostaglandin E synthesis in cultured human umbilical vein smooth muscle cells.
作者信息
Alexander R W, Gimbrone M A
出版信息
Proc Natl Acad Sci U S A. 1976 May;73(5):1617-20. doi: 10.1073/pnas.73.5.1617.
Abstract
Cultured human umbilical vein smooth muscle cells secreted 1.26 +/- 0.20 mug of immunoreactive prostaglandin E (iPGE) per mg of cell protein per 24 hr (mean +/- SEM). In indomethacin, an inhibitor of prostaglandin synthesis, abolished greater than 95% of this basal iPGE production (ID50 = 1.8 nM).
摘要
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